PulseDIA is a patented technique owned by Westlake Omics. This technology divides a DIA window into several windows with narrower ranges of m/zs and evenly allocates them to various spectrometric methods for acquisition. The one sample would be divided into multiple short gradient groups before entering the system. Each group generates its unique spectrometric windows, the data of which are then combined and analyzed altogether, resulting in more identifications of peptides.
Application Scenarios: Suitable for clinical cohort studies with the need of highest depth proteomics analysis.
Mass Spectrometers:
timsTOF Pro
Bruker Orbitrap Exploris™ 480
Reference:
Pulsed Gas-Phase Fractionation. Journal of Proteome Research. 2021.20(1):279-288.
PulseDIA is a patented technique owned by Westlake Omics. This technology divides a DIA window into several windows with narrower ranges of m/zs and evenly allocates them to various spectrometric methods for acquisition. The one sample would be divided into multiple short gradient groups before entering the system. Each group generates its unique spectrometric windows, the data of which are then combined and analyzed altogether, resulting in more identifications of peptides.
Application Scenarios: Suitable for clinical cohort studies with the need of highest depth proteomics analysis.
Mass Spectrometers:
timsTOF Pro
Bruker Orbitrap Exploris™ 480
Application Scenarios: Suitable for clinical cohort studies with the need of highest depth proteomics analysis.
Mass Spectrometers: timsTOF Pro, Bruker Orbitrap Exploris™ 480
Reference:
Pulsed Gas-Phase Fractionation. Journal of Proteome Research. 2021.20(1):279-288.
